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翟雁冰

翟雁冰

助理教授/特别副研究员

学科生物医学工程

方向小型质谱仪研发及其临床应用

电子邮件zhaiyanbing@bit.edu.cn

办公地址:北京市海淀区中关村南大街5号北京理工大学临建楼(图书馆前)

个人简介


2018年博士毕业于北京理工大学生物医学工程专业,同期留校进入化学工程与技术流动站从事博士后研究工作,获得“北京理工大学优秀博士后”荣誉称号2021年1月博士后出站后留校任教至今。长期致力于小型质谱仪研发与应用,开发了世界首款连续大气压接口小型质谱仪及多项高性能小型质谱关键技术,部分技术已进入产业化阶段。近五年来,在本领域重要及顶级期刊发表SCI论文10余篇,申请或授权专利5项,参与获得2017年中国分析测试协会科学技术一等奖。主持博士后基金项目1项、国家自然科学基金项目1项,并参与国家自然科学基金面上项目、国家自然科学基金仪器专项、科技部重点研发计划等多个项目。

教育/培训经历


2009.9-2012.6北京理工大学生命学院生物工程系本科

2013.9-2018.3北京理工大学生命学院生物医学工程系博士研究生

工作经历


2018.3-2021.1北京理工大学生命学院博士后

2021.1-至今北京理工大学英国威廉希尔公司助理教授/特别副研究员

研究领域


质谱分析

小型质谱仪研发与临床应用

所获奖励/荣誉


l 2021年1月,获北京理工大学“2020年度优秀博士后”

l 2017年,获工信部“工信创业奖学金一等奖”;

l 20152017年,获教育部“博士研究生国家奖学金”2次。

参与项目


1、国家自然科学基金青年项目,22004007基于亚真空气电耦合场理论的小型质谱高灵敏技术研究,2021.01-2023.12,24万元,主持

2、第64批中国博士后科学基金面上资助(一等资助),2018M640071,高灵

敏分析微型质谱仪关键技术研究,2019.01-2021.12,8万元,主持

3、国家自然科学基金面上项目,21874016,正弦波频率扫描小型离子

谱仪关键技术研究,2019.01-2022.12,66万元,课题负责人

4、北京理工大学研究生科技创新活动专项计划,微生物原位检测激光质谱

仪,2016.01-2016.12,1万元,主持

5、国家自然科学基金重点项目,61635003,高空间分辨激光差动共焦拉

光谱-LIBS-质谱物质组分测量及形态成像方法研究,2017.01-2021.12,270万

元,参与

6、北京市自然科学基金,L160005,用于超痕量有毒气体现场快速检测的微

型质谱仪高灵敏真空离子源的研制,2016.7-2019.6,29万元,参与


SCI Journal paper

1. Xiangzhi Meng, Caowei Tang, Changxin Zhang, Dayu Li, Wei Xu and Yanbing Zhai*, “A Brick mass spectrometer with photoionization for direct analysis of volatile compounds”, Journal of the American Society for Mass Spectrometry, 2020, 31, 4, 961-968.

2. Yanbing Zhai, Qian Xu, Yang Tang, Siyu Liu, Dayu Li, Wei Xu*, “Boosting the Sensitivity and Selectivity of a Miniature Mass Spectrometer Using a Hybrid Ion Funnel”, Analytical Chemistry, 2019, 91, 7911-7919.

3. Zuqiang Xu, Hanyan Wu, Yang Tang, Wei Xu*, and Yanbing Zhai*, “Electric Modeling and Characterization of Pulsed High Voltage Nano-Electrospray Ionization Sources”, Journal of Mass Spectrometry, 2019, 54, 583-591.

4. Siyu Liu, Jia Zuo, Yaowen Lu, Lijuan Gao, Yanbing Zhai*, and Wei Xu*, “Direct Bacteria Analysis Using Laserspray Ionization Miniature Mass Spectrometry”, Analytical and Bioanalytical Chemistry, 2019, 411, 4031-4040.

5. Yanbing Zhai, Siyu Liu, Lijuan Gao, Lili Hu, and Wei Xu*, “Direct Biological Sample Analyses by Laserspray Ionization Miniature Mass Spectrometry”, Analytical Chemistry, 2018, 90, 5696−5702.

6. Xiangzhi Meng, Xiaohua Zhang, Yanbing Zhai* and Wei Xu*, “Mini 2000: A Robust Miniature Mass Spectrometer with Continuous Atmospheric Pressure Interface”, Instruments, 2018 2 (1), 2.

7. Qi Guo, Lijuan Gao, Yanbing Zhai* and Wei Xu*, “Recent Developments of Miniature Ion Trap Mass Spectrometers”, Chinese Chemical Letters, 29(11),1578-1584.

8. Yanbing Zhai, Xiaohua Zhang, Hualei Xu, Yongchang Zheng, Tao Yuan and Wei Xu*, “Mini Mass Spectrometer Integrated with a Miniature Ion Funnel”, Analytical Chemistry, 2017, 89, 4177-4183.

9. Yanbing Zhai, Ting Jiang, Guangyan Huang, Yongzheng Wei, and Wei Xu*, “An Aerodynamic Assisted Miniature Mass Spectrometer For Enhanced Volatile Sample Analysis”, Analyst, 2016, 141, 5404 - 5411.

10. Yanbing Zhai, Yan Feng, Yongzheng Wei, Yuzhuo Wang, and Wei Xu*, “Development of A Miniature Mass Spectrometer with Continuous Atmospheric Pressure Interface”, Analyst, 2015, 140, 3406-3414.

11. Xianshuang Meng, Yanbing Zhai, Wenfeng Yuan, Yueguang Lv, Qing Lv, Hua Bai, Zengyuan Niu, Wei Xu, Qiang Ma, “Ambient Ionization Coupled with a Miniature Mass Spectrometer for Rapid Identification of Unauthorized Adulterants in Food”, Journal of Food Composition and Analysis, 2020, 85: 103333.

12. Zuqiang Xu, Ting Jiang, Qian Xu, Yanbing Zhai, Dayu Li, Wei Xu*, “Pseudo-Multiple Reaction Monitoring (Pseudo-MRM) Mode on the “Brick” Mass Spectrometer, Using the Grid-SWIFT Waveform”, Analytical Chemistry, 2019, 91, 21, 13838-13846.

13. Ting Jiang, Hongjia Zhang, Yang Tang, Yanbing Zhai, Wei Xu, Hualei Xu, Xinying Zhao, Dayu Li* and Wei Xu*, “A Brick Mass Spectrometer Driven by a Sinusoidal Frequency Scanning Technique”, Analytical Chemistry, 2017, 89 (10), pp 5578–5584.

14. Ting Jiang, Muyi He, Dan Guo, Yanbing Zhai, Wei Xu*, “Ion Collision Cross Section Analyses in Quadrupole Ion Traps Using Filter Diagonalization Method: A Theoretical Study”, Physical Chemistry Chemical Physics, 2016, 18, 12058-12064.

15. Yuzhuo Wang, Xiaohua Zhang, Yanbing Zhai, You Jiang,Xiang Fang, Mingfei Zhou, Yulin Deng and Wei Xu*, “Mass Selective Ion Transfer and Accumulation in Ion Trap Arrays”, Analytical Chemistry, 2014, 86, 10164−10170.

专利

[1] 徐伟,卞存娟,翟雁冰,方向,熊行创,江游, 一种大气压接口的离子源系统以及质谱仪, 中国, 授权号ZL2013104852186

[2] 徐伟,翟雁冰,方向, 种质谱分析安检系统, 中国, 授权号ZL201620099118.9

[3] 徐华磊,翟雁冰,徐伟,一种离子漏斗和质谱检测系统,中国,授权号201620034817.5

[4] 翟雁冰,徐伟,一种离子漏斗装置和质谱检测系统,中国,申请号201910432451.5

[5] 徐伟,张小华,翟雁冰,一种防化侦察方法和系统,中国,申请号201710112352.X

Personal Resume


Education Background


B.E. in Bioengineering, Beijing Institute of Technology, 2009-2013

PH.D in Biomedical Engineering, Beijing Institute of Technology, 2013-2018

Positions and Employment


Assistant Professor

Research and Teaching Interest


l Mass spectrometry

l Development of miniature mass spectrometer for POCT

Honors and Awards


l Excellent Postdoctoral of Beijing Institute of Technology, 2021

l Entrepreneurship scholarship by Ministry of industry and information technology, 2017

l National scholarship for doctoral students, 2015&2017